New research on the DNA-damaging effects of the popular herbicide known as Roundup® indicates that it can do significant harm to fish even after short-term, environmentally low concentration exposures in the parts per billion range (μg /L).[i]
Published this month (July, 2012) in the journal Environmental Monitoring and Assessments researchers set out to evaluate the genotoxic effects that the herbicide Roundup®, and its primary ingredient glyphosate, can have on a species of catfish known as Corydorasa paleatus. When exposed to minute concentrations of Roundup (at a concentration of 6.67 μg/L, corresponding to 3.20 μg/L glyphosate) for 3,6 and 9 days, the following effects were observed: “[T]he comet assay showed a high rate of DNA damage in group exposed to Roundup(®) for all treatment times, both for blood and hepatic cells.” The researchers summarized their findings:
We conclude that for the low concentration used in this research, the herbicide shows potential genotoxic effects. Future research will be important in evaluating the effects of this substance, whose presence in the environment is ever-increasing.
First, it is very important to understand how low a μg /L or parts per billion concentration is. One way to visualize it is to think of one drop in one billion drops of water, or what amounts to one drop of water in an entire swimming pool.[ii]
Owing to the fact that glyphosate is now a ubiquitous contaminant in our environment, having been found in most U.S. air and rain samples tested,[iii] as well as being measured beyond the limit of quantification (higher than 2.5 ug/L) in 41% of 140 groundwater samples collected from Catalonia Spain, this new finding has profound implications for environmental and human health alike. With over 88,000 tons of the stuff used in the US in 2007, according to the USGS, and with an ever-expanding volume being applied to increasingly glyphosate-resistant GM crops, the problem of exposure is only going to get worse in the future – that is, if we continue to support the growth of glyphosate-dependent GM crop industries.
Monsanto, the originator of glyphosate and its most popular branded formulation, Roundup®, once marketed their herbicide “as safe as table salt,” and claimed it was “highly biodegradable.” These claims have now been disproved. Like Agent Orange, another Monsanto co-creation (along with Dow Chemicals, and several other government contractors), this herbicide exhibits a broad range of biocidal (life-killing) properties. (Note: the concept of a “weedkiller” is absurd. These chemicals do not selectively kill only targeted plants. Also, a “weed” is simply a plant whose virtues we have yet discovered [Emerson], or which is encroaching on a plant we favor).
Some of the ways in which glyphosate formulations have been experimentally confirmed to disrupt, mutate, alter or kill are as follows
- Aromatase Disruptor
- Cell Cycle Inhibitor
- Endocrine Disrupter
- Endocrine Disruptor: Testes
- Teratrogenic (Birth Defect Causing)
Of all the adverse health effects listed here, the genotoxicity (DNA-damaging) of glyphosate is the most concerning, and the most consistently supported by the evidence. We have 16 studies on our database substantiating this connection alone, and these studies involve human cell line and animal research as well. DNA-damage has, in fact, been considered the primary factor in carcinogenesis for well over half a century, that is, ever since the multi-mutation theory on cancer was first conceived by Carl O. Nordling in 1953.
If, as accumulating research indicates, the world’s most popular herbicide is contributing to cancer, and that all GM-produced food which is engineered “Roundup Ready” and therefore saturated with glyphosate residues is also a cancer risk, the increasingly global food hegemony of biotech corporations such as Monsanto will be halted in its tracks. Could the growing recognition that glyphosate-based herbicides are contributing to cancer be one reason why Monsanto has been ramping up its funding of privately contracted published research explicitly refuting the accumulating glyphosate/Roundup-cancer connection?
While the pseudo-scientific technocratic dictatorship holds the “weight of the evidence” toxicological risk assessment standard against exposed populations, compelling them to prove that the harms of agrochemicals to human and environmental health outweigh their purported benefits, those of us with a modicum of common sense, and even a layman’s understanding of the precautionary principle, i.e. if there is preliminary evidence a chemical to which we are exposed is unsafe, regulate it accordingly, can vote with our forks and dollars and stop spending our money on GM-containing and/or GM-assocciated foods and products. Also, support the California GMO labeling initiative.
For additional research and articles visit our Health Guide: GMO Research
[i] Nédia de Castilhos Ghisi, Marta Margarete Cestari Genotoxic effects of the herbicide Roundup(®) in the fish Corydoras paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure. Environ Monit Assess. 2012 Jul 22. Epub 2012 Jul 22. PMID: 22821326
[iii] Feng-chih Chang, Matt F Simcik, Paul D Capel. Occurrence and fate of the herbicide glyphosate and its degradate aminomethylphosphonic acid in the atmosphere. Environ Toxicol Chem. 2011 Mar;30(3):548-55. Epub 2011 Jan 19. PMID: 21128261
Article Contributed by Sayer Ji, Founder of GreenMedInfo.com.
Sayer Ji is an author, researcher, lecturer, and advisory board member of the National Health Federation. He founded Greenmedinfo.com in 2008 in order to provide the world an open access, evidence-based resource supporting natural and integrative modalities. It is internationally recognized as the largest and most widely referenced health resource of its kind.